A High-Performance Liquid Chromatographic (HPLC) Method for the Determination of Amlodipine Drug in Dosage form Using 1,2-Naphthoquine-4-Sulfonate (NQS)

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A High-Performance Liquid Chromatographic (HPLC) Method for the Determination of Amlodipine Drug in Dosage form Using 1,2-Naphthoquine-4-Sulfonate (NQS)

A rapid, simple and sensitive high-performance liquid chromatographic (HPLC) method for determination of Amlodipine (AML) using sodium 1,2-naphthoquinone4-sulfonate (NQS) has been developed. The method is based on the formation of a brown color product from the reaction between AML and NQS. The nucleophilic substitution reaction proceeds quantitatively at pH 13 buffer solution with absorption m...

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ژورنال

عنوان ژورنال: Journal of Analytical & Pharmaceutical Research

سال: 2017

ISSN: 2473-0831

DOI: 10.15406/japlr.2017.05.00163